The COVID-19 pandemic in 2020 has endangered many human lives in almost every country in the world. The search for ways to prevent or reduce the negative impact of coronavirus infection is nowadays a priority area of scientific research.
Treatment of coronavirus infection
Patients with asymptomatic or mild coronavirus form are treated at home. However, they are under medical supervision and can get recommendations about treatment of coronavirus infection from their healthcare providers. A patient with a mild course of the coronavirus COVID-19 can be totally cured even in a week. Now the guidelines for treatment COVID-19 include drugs such as:
- Lopinavir and Ritonavir;
- As well as interferon drugs – some of them are used to treat malaria and other protozoal infections.
As you can see, antiviral drugs form the basis of treatment. Besides medications, it is recommended to maintain a healthy lifestyle. The most important rule for a speedy recovery is to drink more water. This is necessary for the natural process of flushing out all toxins from the body. In addition, it is necessary to ventilate the room more often, as well as establish a healthy diet to strengthen the immune system. Treatment for patients with severe COVID form is hospitalization and “supportive care”. That is, medical care is aimed at relieving symptoms and solving those problems that arise in connection with the infection. Most often, a severe form of coronavirus is accompanied by bilateral pneumonia. In this case, doctors provide oxygen therapy, invasive lung ventilation, and mechanical lung ventilation for the treatment of pulmonary inflammation with coronavirus.
Is there a vaccine for COVID-19?
There is no officially proved COVID-19 vaccine. Scientists around the world are actively working on developing a vaccine against the SARS-Cov-2 coronavirus. At the same time, it is possible that already existing drugs can help in the fight against this disease. Nowadays, scientists are testing three groups of drugs that may help patients with COVID-19. These are antiviral drugs, immunomodulators, and respiratory agents. Antiviral drugs prevent the virus from entering the lung cells or preventing them from multiplying. These drugs are used to treat hepatitis C, as well as HIV, Ebola, and, not least, SARS and MERS. The second group of drugs – immunomodulators – is used to limit the overreaction of the immune system. Such drugs are used in the treatment of arthritis or diseases accompanied by intestinal inflammation. The third group – respiratory agents – are the drugs that ensure continuous stable oxygen transfer to the blood by lungs. In the search for a vaccine, scientists are now actively using supercomputers. The IBM AC922 Summit supercomputer used by ORNL researchers has identified 77 drug compounds that can prevent the spread of coronavirus. In the course of further research and experiments, scientists will be able to test the effectiveness of the identified chemical compounds in the fight against COVID-19. It can also become a basement of the antiviral vaccine.
Development of vaccine by Russian scientists
One of the most powerful supercomputers in Russia, Lomonosov-2, has joined the fight against coronavirus. According to the researchers, a potential drug for coronavirus infection will affect the active centers of the target proteins of the SARS-CoV-2 virus and block it. The Lomonosov-2 supercomputer will significantly speed up the search for a drug: it will select molecules by the docking method – molecular modeling. The first such molecules have already been discovered. But what is found on the computer still needs to be confirmed during the experiment, and then checked for real viruses. The next step is the development of the most promising and safe drugs, as well as the determination of the composition, dose, and method of using the future vaccine. Soon, scientists predict the release of a complete vaccine for coronavirus infection treatment.